primary antibodies include anti brca1 (Cell Signaling Technology Inc)
Structured Review

Primary Antibodies Include Anti Brca1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 449 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/primary antibodies include anti brca1/product/Cell Signaling Technology Inc
Average 96 stars, based on 449 article reviews
Images
1) Product Images from "Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs."
Article Title: Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs.
Journal: Frontiers in genetics
doi: 10.3389/fgene.2015.00242
Figure Legend Snippet: FIGURE 1 | Putative miR-15/107 targets within the BRCA1 CDS. (A) Schematic representation of protein-coding BRCA1 transcript. (B) Density function and cumulative distribution of CDS length across all human coding mRNAs. (C) The rna22-predicted target site for the miR-15/107 group together with the corresponding miRNA:mRNA heteroduplexes.
Techniques Used:
Figure Legend Snippet: FIGURE 2 | Suppression of BRCA1 mRNA by miR-15/107 miRNAs. Cell lines transfected with miR-15/107 miRNA precursors show a significant decrease in the amount of available BRCA1 transcript 48 h post-transfection as detected by qRT-PCR. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 compared to control scramble miR by Student’s t-test, n = 3 in each group.
Techniques Used: Transfection, Quantitative RT-PCR, Control
Figure Legend Snippet: FIGURE 4 | Sequestration of miR-15/107 miRNAs impacts BRCA1 mRNA. Cells transfected with luciferase reporter plasmids containing antisense (as) miRNA sequences or predicted wild type (WT) BRCA1 miR-15/107 MRE demonstrate varying levels of BRCA1 expression rescue. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 compared to control by Student’s t-test, n = 3 in each group.
Techniques Used: Transfection, Luciferase, Expressing, Control
Figure Legend Snippet: FIGURE 5 | Translational suppression of BRCA1 by miR-15/107 miRNAs. Western immunoblots from hTERT-HPNE, HCT-116, and MIA PaCa-2 cells demonstrate relative levels of BRCA1 protein expression at 72 h post-transfection with control scramble miRNA and anti-miR precursors, miRNA and anti-miR precursors, or siBRCA1 control.
Techniques Used: Western Blot, Expressing, Transfection, Control